Jan 19, 2017

Sometimes, you just need another clinical trial

Alton Strupp / The Courier-Journal via AP

The FDA just put out a report that's making the rounds among health care wonks. It's about 22 clinical trials of new drugs where the results in the early trials were wildly different than they were in the later, broader ones.

Here's what Joshua Sharfstein, a former FDA deputy commissioner and former secretary of the Maryland health department, tweeted about the report:

Why it matters: It's likely to provide new ammunition to the FDA's defenders as Republicans in Congress, and some Democrats, push for speedier approvals of new drugs. The report listed cases where the Phase 3 trials — which are conducted on broader groups of people than the earlier Phase 2 trials — showed that the new drugs might not be effective or safe, or both.

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Police officers grapple with protesters in Atlanta. Photo: Elijah Nouvelage/Getty Images

Police used tear gas, rubber bullets and pepper spray as the protests sparked by the killing of George Floyd spread nationwide on Friday evening.

The big picture: Police responded in force in cities ranging from Atlanta to Des Moines, Houston to Detroit, Milwaukee to D.C. and Denver to Louisville. In Los Angeles, police declared a stretch of downtown off limits, with Oakland issuing a similar warning.

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Supreme Court sides with California on coronavirus worship service rules

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Why it matters: This is a setback for those seeking to speed the reopening of houses of worship, including President Trump.

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Coronavirus dashboard

Illustration: Sarah Grillo/Axios

  1. Global: Total confirmed cases as of 10 p.m. ET: 5,923,432— Total deaths: 364,836 — Total recoveries — 2,493,434Map.
  2. U.S.: Total confirmed cases as of 10 p.m. ET: 1,745,930 — Total deaths: 102,808 — Total recoveries: 406,446 — Total tested: 16,099,515Map.
  3. Public health: Hydroxychloroquine prescription fills exploded in March —How the U.S. might distribute a vaccine.
  4. 2020: North Carolina asks RNC if convention will honor Trump's wish for no masks or social distancing.
  5. Business: Fed chair Powell says coronavirus is "great increaser" of income inequality.
  6. 1 sports thing: NCAA outlines plan to get athletes back to campus.