Researchers have used a detailed genetic analysis of the most common form of brain cancer in children (called medulloblastoma) to devise potentially new therapeutic strategies. If further tests confirm the findings, it could lead to novel treatments to mitigate the more severe side effects of cancer treatment.

Why it matters: Brain cancer in children is a profoundly difficult burden for both parents and doctors alike. The current medical treatments and therapies for this type of brain cancer in children have unpleasant side effects that can impair a child's quality of life following the treatments, the researchers wrote in Nature.

Compounding the problem is the fact that this type of cancer has several different genetic sub-types, which means that the current treatments are forced to take a "one-size-fits-all" approach with chemotherapy that leads to potentially toxic side effects. The new research should help scientists properly characterize each of these genetic sub-types, which in turn may allow for targeted chemotherapy treatment strategies that could minimize the toxic side effects.

What they found: The researchers looked at the genetic foundations and sequencing for 491 individual medulloblastoma cases; and at the expression of particular genes in another 1,256 cases. From there they were able to characterize all of the cancer sub-groups and the different genetic alterations associated with them. They even found several new sub-types that had not been previously identified, which they said shows this type of brain cancer in children should be considered a collection of diseases rather than just one cancer.

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Gulf Coast braces for Zeta after storm strengthens into hurricane

Hurricane Zeta's forecast path. Photo: National Hurricane Center

Louisiana Gov. Gov. John Bel Edwards (D) declared a state of emergency Monday as Zeta strengthened into a hurricane and threatened Mexico's Yucatan Peninsula as it moved towards the U.S. Gulf Coast.

The state of play: Zeta was expected to make landfall on the northern part of the Yucatan Peninsula Monday night, bringing with it a "dangerous storm surge" and "heavy rainfall" as it moved into the Gulf of Mexico, the National Hurricane Service said.

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Supreme Court rejects request to extend Wisconsin absentee ballot deadline

Photo: Saul Loeb/AFP via Getty Images

The Supreme Court in a 5-3 decision Monday rejected an effort by Wisconsin Democrats and civil rights groups to extend the state's deadline for counting absentee ballots to six days after Election Day, as long as they were postmarked by Nov. 3.

Why it matters: All ballots must now be received by 8 p.m. on Election Day in Wisconsin, a critical swing state in the presidential election.