California Gov. Gavin Newsom (D). Photo by Justin Sullivan/Getty Images

California Gov. Gavin Newsom (D) marked his 100th day in office Wednesday with the announcement that Los Angeles County has joined the state's effort to negotiate lower prescription drug prices with pharmaceutical companies.

Why it matters: Newsom signed an executive order when he took office directing state officials to establish a program that would "ultimately be the nation’s largest single-purchaser system for prescription drugs." Los Angeles County is the first outside participant of his initiative, the San Francisco Chronicle reports.

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Doomsday has arrived for tens of thousands of workers

Illustration: Sarah Grillo/Axios

Federal coronavirus aid for airlines expires on Thursday with no renewal in sight, meaning massive layoffs for the industry aren't far behind.

The big picture: Airline workers aren't alone on the unemployment line. Oil companies, tire manufacturers, book publishers and insurers are among those that have announced tens of thousands of layoffs. Federal aid through the CARES Act earlier this year delayed most layoffs — until now.

2 hours ago - Science

How the brain handles the unknown

Illustration: Sarah Grillo/Axios

Uncertainty can be hard for humans. It drives anxiety, an emotion neuroscientists are trying to understand and psychologists are trying to better treat.

Why it matters: Under the threat of a virus, job insecurity, election uncertainty, and a general pandemic life-in-limbo that is upending school, holidays and more, people are especially anxious.

Updated 2 hours ago - Politics & Policy

Coronavirus dashboard

Illustration: Eniola Odetunde/Axios

  1. Global: Total confirmed cases as of 3 p.m. ET: 34,103,279 — Total deaths: 1,016,167 — Total recoveries: 23,694,869Map.
  2. U.S.: Total confirmed cases as of 3 p.m. ET: 7,255,546 — Total deaths: 207,374 — Total recoveries: 2,840,688 — Total tests: 103,939,667Map.
  3. Politics: House prepares to pass revised COVID relief bill as White House talks hit roadblock.
  4. Health: Health officials urge flu shots, warning of "twindemic" with COVID-19 — Coronavirus infections rise in 25 states.
  5. Business: Remdesivir is good business for Gilead.