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National Cancer Institute

Scientists are proposing a new way to fight solid cancer tumors by interfering with blood vessels surrounding them to shut off the tumor's supply of oxygen and nutrients. The new research could lead to a therapy that combines two different mechanisms used by immune cells to halt the growth of cancer tumors.

The background: The immune system is the most powerful weapon against diseases that we know. Medical researchers have triggered the immune system to fight cancer cells floating in the blood stream, but not successfully on solid tumors.

How it might work: T-cells are a special type of immune cell. They produce both interferon gamma and something called tumor necrosis factor (TNF). Working together, TNF can burst the blood vessels around a cancer, which allows interferon gamma to cut off the blood supply. The researchers tested it on genetically modified mice in a clinical lab setting. It didn't kill the cancer cells, but it kept the disease from progressing by stopping the growth of tumors.

Go deeper

Updated 2 hours ago - World

Islamic State claims responsibility for deadly bombing in southern Afghanistan

The mosque after the explosion in southern Kandahar province on Oct. 15. Photo: Murteza Khaliqi/Anadolu Agency via Getty Images

The Islamic State group claimed responsibility for a massive blast that tore through a crowded Shiite mosque in the southern Afghan city of Kandahar on Friday, killing at least 47 people and injuring dozens more, AP reports.

Why it matters: Friday's attack was the deadliest to strike Afghanistan since the U.S. withdrew its troops from the region and is the second major attack on a Shiite mosque in a week, underscoring the Taliban's growing security threat from other militant groups.

New wave of strikes will test worker power

Illustration: Sarah Grillo/Axios

Thousands of John Deere workers hit the picket line this week after the union smacked down a new worker contract from the farm and equipment maker.

Why it matters: There’s a wave of worker angst spreading across the country. They wield new power that’s come with a historic worker shortage.

Bryan Walsh, author of Future
5 hours ago - Technology

The smart city comes of age

Illustration: Aïda Amer/Axios

Better sensors, more intelligent AI, and the coming wave of 5G wireless could finally fulfill the promise of the smart city.

Why it matters: How we organize, run and power our cities will be increasingly important in the years ahead, as urbanization expands and the damaging effects of climate change compound.