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Photo: RADEK MICA/AFP via Getty Images

Moderna on Tuesday announced that its coronavirus vaccine was found to be safe and 100% effective at protecting against COVID-19 in a Phase 3 trial of more than 3,700 participants between the ages of 12 and 17.

Why it matters: Moderna CEO Stéphane Bancel said the company plans to submit its data to global regulators in early June, paving the way for an emergency use authorization for adolescents.

  • If approved by the U.S. Food and Drug Administration, it would increase the number of available vaccines for teenagers before the school year starts, per CNBC.
  • Moderna's vaccine is the second to show high efficacy in younger age groups, following Pfizer, which received an FDA emergency use authorization for adolescents earlier this month.

Details: Moderna's clinical trial included 3,732 adolescent participants ages 12 to 17, with one group receiving the vaccine and another receiving a placebo.

  • No virus cases were observed in the vaccine group after two doses, "resulting in a vaccine efficacy of 100% starting 14 days after the second dose," according to the company.
  • The vaccine was found to be 93% effective after one dose.

What to watch: The study is ongoing, and participants will continue to be monitored for 12 months after their second injection. Moderna says the results are subject to change based on ongoing data collection.

  • The company plans to submit their results to a peer-reviewed publication.

Go deeper

Sep 1, 2021 - Health

The bureaucracy pushes back on Biden's booster plan

Illustration: Annelise Capossela/Axios

Signs are beginning to publicly emerge that the scientists responsible for bureaucratic decision-making about drug policy are frustrated with how the White House has handled coronavirus vaccine boosters.

Why it matters: The Biden administration has made clear that its priority, when it comes to boosters, is to stay ahead of the virus. But in doing so, it's also getting ahead of the process by which such decisions are usually made.

Sep 1, 2021 - Health

Report: U.S. has discarded over 15 million COVID vaccine doses since March

A nurse reaches for a vial of the Pfizer-BioNTech COVID-19 vaccine at a pop-up vaccine clinic in the Arleta neighborhood of Los Angeles. Photo: Robyn Beck/AFP via Getty Images

The U.S. has discarded at least 15.1 million doses of COVID-19 vaccines since March 1, according to government data obtained by NBC News.

Why it matters: The data comes as the Delta variant spreads rapidly across the country, and after the Biden administration announced plans to roll out booster shots — renewing the need for an ample vaccine supply.

Sep 1, 2021 - Sports

Washington Nationals, VP Bob Boone part ways after vaccine mandate

Washington Nationals VP Bob Boone. Photo: Alex Trautwig/MLB via Getty Images

The Washington Nationals and Vice President Bob Boone are parting ways over the team's vaccine mandate for all full-time staff, the Washington Post reported on Wednesday.

Driving the news: The Nationals informed staff of the vaccine mandate on Aug. 14. Employees had until Aug. 26 to provide either proof of full vaccination or one dose of the vaccine or apply for an exemption, per WashPost.

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