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The FDA today starts its two-day meeting to hash out whether it should limit or even remove high-dose opioids from the market.

The big picture: The Centers for Disease Control and Prevention says "higher dosages of opioids are associated with higher risk of overdose and death," and people really shouldn't take painkillers that exceed a certain limit.

  •  Some opioids, like the OxyContin 80 mg tablet, vastly exceed the CDC's suggested limit with just one pill.

Yes, but: Patients battling chronic pain are worried they will be worse off if they have taper to lower doses.

Guess who’s presenting: RADARS, which has advocated against restricting prescriptions of high-dose painkillers. Ted Cicero, a paid researcher for RADARS, will talk about "understanding opioid trajectories."

Go deeper: Watch the FDA's webcast

Go deeper

47 mins ago - Politics & Policy

Biden's latest executive order: Buy American

President Joe R. Biden speaks about the economy before signing executive orders in the State Dining Room at the White House on Friday, Jan 22, 2021 in Washington, DC. (Photo by Jabin Botsford/The Washington Post via Getty Images)

President Joe Biden will continue his flurry of executive orders on Monday, signing a new directive to require the federal government to “buy American” for products and services.

Why it matters: The executive action is yet another attempt by Biden to accomplish goals administratively without waiting for the backing of Congress. The new order echoes Biden's $400 billion campaign pledge to increase government purchases of American goods.

Tech digs in for long domestic terror fight

Illustration: Sarah Grillo/Axios

With domestic extremist networks scrambling to regroup online, experts fear the next attack could come from a radicalized individual — much harder than coordinated mass events for law enforcement and platforms to detect or deter.

The big picture: Companies like Facebook and Twitter stepped up enforcement and their conversations with law enforcement ahead of Inauguration Day. But they'll be tested as the threat rises that impatient lone-wolf attackers will lash out.

The pandemic could be worsening childhood obesity

Illustration: Aïda Amer/Axios

The 10-month long school closures and the coronavirus pandemic are expected to have a big impact on childhood obesity rates.

Why it matters: About one in five children are obese in the U.S. — an all-time high — with worsening obesity rates across income and racial and ethnic groups, data from the National Health and Nutrition Examination Survey show.