The FDA today starts its two-day meeting to hash out whether it should limit or even remove high-dose opioids from the market.

The big picture: The Centers for Disease Control and Prevention says "higher dosages of opioids are associated with higher risk of overdose and death," and people really shouldn't take painkillers that exceed a certain limit.

  •  Some opioids, like the OxyContin 80 mg tablet, vastly exceed the CDC's suggested limit with just one pill.

Yes, but: Patients battling chronic pain are worried they will be worse off if they have taper to lower doses.

Guess who’s presenting: RADARS, which has advocated against restricting prescriptions of high-dose painkillers. Ted Cicero, a paid researcher for RADARS, will talk about "understanding opioid trajectories."

Go deeper: Watch the FDA's webcast

Go deeper

Updated 47 mins ago - Politics & Policy

Supreme Court blocks Alabama curbside voting measure

Photo: Mark Wilson/Getty Images

The Supreme Court on Wednesday evening blocked a lower court order that would have allowed voters to cast ballots curbside at Alabama polling places on Election Day.

Whit it matters: With less than two weeks until Election Day, the justices voted 5-3 to reinstate the curbside voting ban and overturn a lower court judge's ruling designed to protect people with disabilities during the coronavirus pandemic.

Updated 2 hours ago - Politics & Policy

Coronavirus dashboard

Illustration: Aïda Amer/Axios

  1. Politics: Senate Democrats block vote on McConnell's targeted COVID relief bill McConnell urges White House not to strike stimulus deal before election.
  2. Economy: Why the stimulus delay isn't a crisis (yet).
  3. Health: New York reports most COVID cases since MayStudies show drop in coronavirus death rate — The next wave is gaining steam.
  4. Education: Schools haven't become hotspots — San Francisco public schools likely won't reopen before the end of the year.
  5. World: Spain becomes first nation in Western Europe to exceed 1 million cases.

U.S. officials: Iran and Russia aim to interfere in election

Iran and Russia have obtained voter registration information that can be used to undermine confidence in the U.S. election system, Director of National Intelligence John Ratcliffe announced at a press conference Wednesday evening.

Why it matters: The revelation comes roughly two weeks before Election Day. Ratcliffe said Iran has sent threatening emails to Democratic voters this week in states across the U.S. and spread videos claiming that people can vote more than once.