Yes, the Senate's bipartisan Affordable Care Act bill ran into some political roadblocks yesterday. The White House said President Trump, who had taken several positions over the course of the day, is against it. House Speaker Paul Ryan is also against it. And conservatives are against it.
Why it doesn't matter: The story of the Alexander-Murray bill likely won't be over until December, when Congress has to take care of several must-pass bills, in negotiations where Democrats have a lot of leverage.