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Photo: Mandel Ngan/AFP/Getty Images

Sen. John Cornyn (R-Texas) told the Dallas Morning News that he called President Trump on Tuesday to warn him that closing the U.S.-Mexico border would be a “terrible mistake” and that it could “inflict unintended harm on Americans.”

Why it matters: The U.S. exported $265 billion worth of goods to Mexico in 2018, with approximately $1.67 billion in trade daily between the two countries. Produce, as well as the auto, alcohol and oil industries would be particularly strained with a border closure. Trump intends to stop illegal crossings with the closure.

Go deeper

Bryan Walsh, author of Future
1 hour ago - Health

COVID-19 shows a bright future for vaccines

Illustration: Annelise Capossela/Axios

Promising results from COVID-19 vaccine trials offer hope not just that the pandemic could be ended sooner than expected, but that medicine itself may have a powerful new weapon.

Why it matters: Vaccines are, in the words of one expert, "the single most life-saving innovation ever," but progress had slowed in recent years. New gene-based technology that sped the arrival of the COVID vaccine will boost the overall field, and could even extend to mass killers like cancer.

3 hours ago - Health

Beware a Thanksgiving mirage

Illustration: Sarah Grillo/Axios

Don't be surprised if COVID metrics plunge over the next few days, only to spike next week.

Why it matters: The COVID Tracking Project warns of a "double-weekend pattern" on Thanksgiving — where the usual weekend backlog of data is tacked on to a holiday.

Trump pardons Michael Flynn

President Trump with Michael Flynn in 2016. Photo: David Hume Kennerly/Getty Images

President Trump on Wednesday pardoned his former national security adviser Michael Flynn, who pleaded guilty in the Mueller investigation to lying to FBI agents about his conversations with a former Russian ambassador.

Why it matters: It is the first of multiple pardons expected in the coming weeks, as Axios scooped Tuesday night.