Sign up for our daily briefing

Make your busy days simpler with Axios AM/PM. Catch up on what's new and why it matters in just 5 minutes.

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Catch up on coronavirus stories and special reports, curated by Mike Allen everyday

Catch up on coronavirus stories and special reports, curated by Mike Allen everyday

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Denver news in your inbox

Catch up on the most important stories affecting your hometown with Axios Denver

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Des Moines news in your inbox

Catch up on the most important stories affecting your hometown with Axios Des Moines

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Minneapolis-St. Paul news in your inbox

Catch up on the most important stories affecting your hometown with Axios Twin Cities

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Tampa Bay news in your inbox

Catch up on the most important stories affecting your hometown with Axios Tampa Bay

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Charlotte news in your inbox

Catch up on the most important stories affecting your hometown with Axios Charlotte

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!
Expand chart
Data: Institute for Health Metrics and Evaluation; Chart: Andrew Witherspoon/Axios 

Global health funds play a key role in improving the world's health — with the deaths of children under 5 dropping by more than 50% over the past couple decades when investment strengthened, Melinda and Bill Gates told a press conference Wednesday.

Why it matters: Activities from 4 major global funds, which have received almost $10 billion from the Bill and Melinda Gates Foundation since 1999, have proven to offer "enormous" benefits, they said.

Details: Bill said the returns from their investment into GAVI, the Global Fund, the Global Polio Eradication Initiative and Global Financing Facility have been "really fantastic."

  • Deaths from infectious diseases like HIV, malaria and measles have halved from their 1990 levels, a key factor in lowering death rates in the poorest countries.
  • A child born today is half as likely to die before the age of five, compared to if she was born in 2000.
  • Melinda noted that part of the challenge is to help less developed countries improve their infrastructure to be able to access necessary health care — for example, helping Zambia with the logistics of getting bed nets from the port to people who need them. "That's been fixed now," she said.
  • There's been progress on the challenge of producing vaccines faster, particularly for the deadly Ebola and MERS viruses, via public-private coalitions like CEPI, Bill said. He added that they are learning more about vaccines through pharma's interest in immunotherapy for cancer patients.

To be sure: Melinda and Bill didn't only discuss the rosy news.

  • Conquering polio has been a much more drawn-out and expensive battle than they originally anticipated — and it's one that continues to be problematic, they say.
  • The world is nowhere near ready to address a pandemic. "There's still a lot of work needed to be done," Bill said, especially in deciding what the rules would be and how cooperation would work in terms of a global emergency.
  • "Over the next 18 months, all 4 of these are kind of at a critical point where the level of distraction by domestic issues or issues that are confined to the rich world do make us somewhat concerned that the great success story here and the need to renew these resources may not get the attention it deserves," Bill said.

The bottom line: There is a clear delineation in improved results after 2000, when "the world started investing more in global health, and in particular global health institutions," Melinda said. Both said it will be key that governments and private institutions continue investing in these funds for the next couple decades.Go deeper:

Go deeper

Updated 12 hours ago - Politics & Policy

Coronavirus dashboard

Illustration: Eniola Odetunde/Axios

  1. Health: Most vulnerable Americans aren't getting enough vaccine information — Fauci says Trump administration's lack of facts on COVID "very likely" cost lives.
  2. Politics: Biden unveils "wartime" COVID strategyBiden's COVID-19 bubble.
  3. Vaccine: Florida requiring proof of residency to get vaccine — CDC extends interval between vaccine doses for exceptional cases.
  4. World: Hong Kong to put tens of thousands on lockdown as cases surge.
  5. Sports: 2021 Tokyo Olympics hang in the balance.
  6. 🎧 Podcast: Carbon Health's CEO on unsticking the vaccine bottleneck.

Trump impeachment trial to start week of Feb. 8, Schumer says

Senate Majority Leader Chuck Schumer. Photo: The Washington Post via Getty

The Senate will begin former President Trump's impeachment trial the week of Feb. 8, Majority Leader Chuck Schumer announced Friday on the Senate floor.

The state of play: Schumer announced the schedule after reaching an agreement with Republicans. The House will transmit the article of impeachment against the former president late Monday.

13 hours ago - Health

CDC extends interval between COVID vaccine doses for exceptional cases

Photo: Joseph Prezioso/AFP via Getty

Patients can space out the two doses of the coronavirus vaccine by up to six weeks if it’s "not feasible" to follow the shorter recommended window, according to updated guidance from the Centers for Disease and Control and Prevention.

Driving the news: With the prospect of vaccine shortages and a low likelihood that supply will expand before April, the latest changes could provide a path to vaccinate more Americans — a top priority for President Biden.